Niacin Resource Center
Frequently Asked Questions
Niacin is vitamin B3. Stephen's research focuses on niacin's effects on metabolic markers relevant to kidney health, often in combination with sodium bicarbonate.
Stephen studies how niacin, combined with sodium bicarbonate, may support kidney function in chronic kidney disease. His work with W. Todd Penberthy and colleagues is documented in the Research Library.
Flushing occurs when niacin triggers the release of prostaglandins, which dilate small blood vessels near the skin. See the Managing Niacin Flushing guide for details on why it happens and how it's managed.
Flushing niacin (immediate-release nicotinic acid) causes temporary warming and reddening of the skin. Non-flushing or “no-flush” products typically use a different compound that avoids this effect, but may not produce the same metabolic effects.
Anyone considering niacin, especially with existing kidney, liver, or metabolic conditions, should speak with a qualified healthcare professional first and use appropriate lab monitoring before and during use.
The Scientific Evidence page lists the published studies Stephen has co-authored or references, with his commentary presented separately from each study's findings.
Watch
Midlife Wellness NP · ~2024 · 1:45:26
Full podcast episode addressing common niacin myths — including cardiovascular-risk claims — and presenting counter-evidence and benefits.
Kidney/CKD topic: Niacin myths, evidence, and cardiovascular risk
Watch on YouTube →